The queen is working an enchantment to regain her beauty with the aid of her werewolf huntsman with a magic axe, crow familiars, and various creatures in the forest. She needs to drink the blood of 12 young women to regain her beauty, 10 have already been reported missing. Her youthful appearance now only exists in her mirror, the source of her life, as an illusion and nothing more. Her spell granted her immortal life, but not the youth and beauty to go along with it. She did not understand the Plague was carried by wind and soon rotted away as she decayed over the years. The Bubonic plague comes and she builds a high tower to avoid it, while her husband and everyone below her perishes. Long ago, King Childeric I came to the forest to build a city while his Queen experiments with black magic stolen from the pagan locals to gain eternal life. However, they soon discover that it is in fact the work of a real supernatural force: a 500-year-old, Thuringian Queen stealing young girls to restore her own beauty. The Brothers are charged with finding out who is responsible, under the assumption that it is the work of con artists like themselves. Delatombe forces them to solve a mystery: the girls of the small village of Marbaden are going missing and the villagers are convinced that supernatural forces are responsible. Italian torturer Cavaldi captures the two and takes them to the French General Delatombe. In Karlstadt they 'kill' a witch's ghost, after tricking the village. Will and Jake Grimm are traveling con artists who utilise Jake's knowledge of folklore to fool people into paying them to kill monsters in French-occupied Germany during the early 19th century. The Brothers Grimm was finally released on 26 August 2005 with mixed reviews and grossed $105.3 million at the worldwide box office. Gilliam often had on-set feuds with brothers Bob and Harvey Weinstein, which caused the original theatrical release date to be delayed nearly ten months. The film was shot entirely in the Czech Republic.

MGM eventually dropped out as distributor, but decided to co-finance The Brothers Grimm with Dimension Films and Summit Entertainment, while Dimension took over distribution duties. With Gilliam's hiring as director, the script was rewritten by Gilliam and Tony Grisoni, but the Writers Guild of America refused to credit them for their work, thus Kruger received sole credit. In February 2001, Ehren Kruger sold his spec script to Metro-Goldwyn-Mayer (MGM). Supporting characters are played by Peter Stormare, Jonathan Pryce, and Monica Bellucci. However, the brothers eventually encounter a genuine fairy tale curse which requires real courage instead of their usual bogus exorcisms. The film stars Matt Damon, Heath Ledger and Lena Headey in an exaggerated and fictitious portrait of the Brothers Grimm as traveling con-artists in French-occupied Germany, during the early 19th century. The Brothers Grimm is a 2005 adventure fantasy film directed by Terry Gilliam.

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